Five-Year Change in Visceral Adipose Tissue Quantity in a Minority Cohort: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study

Author:

Hairston Kristen G.1,Scherzinger Ann2,Foy Capri1,Hanley Anthony J.3,McCorkle Orita1,Haffner Steven4,Norris Jill M.2,Bryer-Ash Michael5,Wagenknecht Lynne E.1

Affiliation:

1. Wake Forest University School of Medicine, Winston-Salem, North Carolina;

2. University of Colorado Health Sciences Center, Denver, Colorado;

3. Department of Nutritional Sciences, University of Toronto, Toronto, Canada;

4. University of Texas Health Science Center at San Antonio, San Antonio, Texas;

5. University of Oklahoma School of Health Sciences, Oklahoma City, Oklahoma.

Abstract

OBJECTIVE To describe the 5-year change in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) areas. RESEARCH DESIGN AND METHODS Absolute change in VAT and SAT measured by abdominal computed tomography scans has been obtained at a 5-year interval from African Americans (n = 389) and Hispanic Americans (n = 844), aged 20–69 years, in 10-year age-groups. RESULTS Mean 5-year increases in VAT areas in women were 18, 7, 4, 0.4, and −3 cm2 for African Americans and 13, 7, 3, 1, and −15 cm2 for Hispanics, across the 5 age decades (trend not significant). Mean 5-year increases in SAT areas in women were 88, 46, 19, 17, and 14 cm2 for African Americans and 53, 20, 17, 12, and 1 cm2 for Hispanics, across the 5 age decades (P < 0.05 for both). Similar trends have been observed in men. CONCLUSIONS Accumulation of abdominal fat is greatest in young adulthood. These data may be useful in identifying subgroups at risk of type 2 diabetes.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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