Affiliation:
1. Istituto di Semeiotica Medica, Universitä degli Studi di Parma Parma, Italy
2. Cattedra di Endocrinologia e Patologia Costituzionale, Universitä degli Studi di Parma Parma, Italy
Abstract
Insulin-dependent diabetes mellitus (IDDM) induces plasma amino acid (AA) abnormalities, including low alanine and high branched-chain (BCAA). While insulin treatment restores plasma AA pattern, proline, methionine, valine, isoleucine, and total BCAA remain elevated in skeletal muscle intracellular water. This suggests that the restoration of plasma AA concentrations is not a satisfactory index of recovered AA metabolism in IDDM.
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
19 articles.
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