Affiliation:
1. Department of Medicine “B” and the Laboratory of Clinical Biochemistry, Hadassah University Hospital and Hebrew University—Hadassah Medical School Jerusalem, Israel
Abstract
GT and concomitant FFA decreases have been examined in forty-three patients with myocardial infarction below fifty years of age with no history of diabetes, fasting hyperglycemia or glycosuria. The majority had an impaired GT, which was associated, in two thirds of the cases, with a prompt and long-lasting FFA decrease similar to, or exceeding, that of normal subjects. It is suggested that a state of differential effectiveness of insulin exists in a large proportion of patients with myocardial infarction, whereby normal response of adipose tissue persists while glucose utilization of nonadipose tissues is impaired. The association of selective unavailability of insulin with the development of arteriosclerosis is briefly discussed.
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
53 articles.
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