Can a Low–Glycemic Index Diet Reduce the Need for Insulin in Gestational Diabetes Mellitus?

Author:

Moses Robert G.1,Barker Megan1,Winter Meagan1,Petocz Peter2,Brand-Miller Jennie C.3

Affiliation:

1. Illawarra Diabetes Service, South Eastern Sydney and Illawarra Area Health Service, Wollongong, New South Wales, Australia;

2. Department of Statistics, Macquarie University, Sydney, New South Wales, Australia;

3. Human Nutrition Unit, University of Sydney, New South Wales, Australia.

Abstract

OBJECTIVE A low–glycemic index diet is effective as a treatment for individuals with diabetes and has been shown to improve pregnancy outcomes when used from the first trimester. A low–glycemic index diet is commonly advised as treatment for women with gestational diabetes mellitus (GDM). However, the efficacy of this advice and associated pregnancy outcomes have not been systematically examined. The purpose of this study was to determine whether prescribing a low–glycemic index diet for women with GDM could reduce the number of women requiring insulin without compromise of pregnancy outcomes. RESEARCH DESIGN AND METHODS All women with GDM seen over a 12-month period were considered for inclusion in the study. Women (n = 63) were randomly assigned to receive either a low–glycemic index diet or a conventional high-fiber (and higher glycemic index) diet. RESULTS Of the 31 women randomly assigned to a low–glycemic index diet, 9 (29%) required insulin. Of the women randomly assigned to a higher–glycemic index diet, a significantly higher proportion, 19 of 32 (59%), met the criteria to commence insulin treatment (P = 0.023). However, 9 of these 19 women were able to avoid insulin use by changing to a low–glycemic index diet. Key obstetric and fetal outcomes were not significantly different. CONCLUSIONS Using a low–glycemic index diet for women with GDM effectively halved the number needing to use insulin, with no compromise of obstetric or fetal outcomes.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference14 articles.

1. Proceedings of the Fourth International Workshop-Conference on Gestational Diabetes Mellitus;Metzger;Diabetes Care,1998

2. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes;Crowther;N Engl J Med,2005

3. Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association;American Diabetes Association;Diabetes Care,2008

4. A comparison of glyburide and insulin in women with gestational diabetes mellitus;Langer;N Engl J Med,2000

5. Metformin versus insulin for the treatment of gestational diabetes;Rowan;N Engl J Med,2008

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