Ten Years of Improving Glycemic Control in Pediatric Diabetes Care: Data From the Norwegian Childhood Diabetes Registry

Author:

Bratke Heiko12345ORCID,Biringer Eva4,Ushakova Anastasia6,Margeirsdottir Hanna D.378,Kummernes Siv Janne57,Njølstad Pål R.29,Skrivarhaug Torild3578

Affiliation:

1. 1Department of Pediatrics, Haugesund Hospital, Fonna Health Trust, Haugesund, Norway

2. 2Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway

3. 3Oslo Diabetes Research Center, Oslo, Norway

4. 4Department of Research and Innovation, Fonna Health Trust, Haugesund, Norway

5. 5The Norwegian Childhood Diabetes Registry, Division of Childhood and Adolescent Medicine, Oslo University Hospital, Oslo, Norway

6. 6Department of Research, Stavanger University Hospital, Stavanger, Norway

7. 7Division of Childhood and Adolescent Medicine, Oslo University Hospital, Oslo, Norway

8. 8Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

9. 9Child and Youth Clinic, Haukeland University Hospital, Bergen, Norway

Abstract

OBJECTIVE To evaluate, from 2013 to 2022, how HbA1c, the incidence of acute complications, and use of diabetes technology changed at the national level in Norway and how glycemic control was associated with use of diabetes technology, carbohydrate counting, or participation in a quality improvement project. RESEARCH DESIGN AND METHODS This longitudinal observational study was based on 27,214 annual registrations of 6,775 children from the Norwegian Childhood Diabetes Registry from 2013 to 2022. Individuals aged >18 years, those with diabetes other than type 1, and those without HbA1c measurements were excluded. The outcome measure was HbA1c. The predictor variables in the adjusted linear mixed-effects model were 1) the use of diabetes technology, 2) the use of carbohydrate counting for meal bolusing, and 3) whether the patient’s diabetes team participated in a quality improvement project. RESULTS Mean HbA1c decreased from 8.2% (2013) to 7.2% (2021), and the proportion of youth reaching an HbA1c <7.0% increased from 13% (2013) to 43% (2022). Insulin pump use increased from 65% (2013) to 91% (2022). Continuous glucose monitoring (CGM) use increased from 34% (first recorded in 2016) to 97% (2022). Insulin pump, CGM, and carbohydrate counting were associated with lower HbA1c and higher achievement of glycemic targets. Girls had a higher mean HbA1c than boys. Mean HbA1c levels were lower in clinics that participated in a quality improvement project for the following 4 years after the project. CONCLUSIONS Diabetes technology, carbohydrate counting, and systematic quality improvement in pediatric departments led to improved glycemic control.

Funder

South-Eastern Norway Regional Health Authority

Helse Vest

Norges Forskningsråd

Universitetet i Bergen

Novo Nordisk Foundation Center for Basic Metabolic Research

Trond Mohn stiftelse

H2020 European Research Council

Publisher

American Diabetes Association

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