Higher Neighborhood Drivability Is Associated With a Higher Diabetes Risk in Younger Adults: A Population-Based Cohort Study in Toronto, Canada

Author:

den Braver Nicolette R.12ORCID,Beulens Joline W.J.12,Wu C. Fangyun3,Fazli Ghazal S.4,Gozdyra Peter34,Howell Nicholas A.5,Lakerveld Jeroen12,Moin John S.6,Rutters Femke1,Brug Johannes7,Moineddin Rahim36,Booth Gillian L.3458

Affiliation:

1. 1Amsterdam University Medical Centers, Amsterdam, the Netherlands

2. 2Upstream Team, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

3. 3The Institute of Clinical Evaluative Sciences, Toronto, Ontario, Canada

4. 4MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada

5. 5Department of Medicine, University of Toronto, Ontario, Canada

6. 6Department of Family and Community Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

7. 7National Institute for Public Health and the Environment, Bilthoven, the Netherlands

8. 8Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

Abstract

OBJECTIVECar dependency contributes to physical inactivity and, consequently, may increase the likelihood of diabetes. We investigated whether neighborhoods that are highly conducive to driving confer a greater risk of developing diabetes and, if so, whether this differs by age.RESEARCH DESIGN AND METHODSWe used administrative health care data to identify all working-age Canadian adults (20–64 years) who were living in Toronto on 1 April 2011 without diabetes (type 1 or 2). Neighborhood drivability scores were assigned using a novel, validated index that predicts driving patterns based on built environment features divided into quintiles. Cox regression was used to examine the association between neighborhood drivability and 7-year risk of diabetes onset, overall and by age-group, adjusting for baseline characteristics and comorbidities.RESULTSOverall, there were 1,473,994 adults in the cohort (mean age 40.9 ± 12.2 years), among whom 77,835 developed diabetes during follow-up. Those living in the most drivable neighborhoods (quintile 5) had a 41% higher risk of developing diabetes compared with those in the least drivable neighborhoods (adjusted hazard ratio 1.41, 95% CI 1.37–1.44), with the strongest associations in younger adults aged 20–34 years (1.57, 95% CI 1.47–1.68, P < 0.001 for interaction). The same comparison in older adults (55–64 years) yielded smaller differences (1.31, 95% CI 1.26–1.36). Associations appeared to be strongest in middle-income neighborhoods for younger residents (middle income 1.96, 95% CI 1.64–2.33) and older residents (1.46, 95% CI 1.32–1.62).CONCLUSIONSHigh neighborhood drivability is a risk factor for diabetes, particularly in younger adults. This finding has important implications for future urban design policies.

Funder

Public Health Research Institute

European Foundation for the Study of Diabetes (EFSD) Albert Renold Travel Fellowship

Canadian Institutes of Health Research

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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