Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Author:

Davies Melanie J.12ORCID,Aroda Vanita R.3ORCID,Collins Billy S.4ORCID,Gabbay Robert A.5ORCID,Green Jennifer6ORCID,Maruthur Nisa M.7ORCID,Rosas Sylvia E.8ORCID,Del Prato Stefano9ORCID,Mathieu Chantal10ORCID,Mingrone Geltrude111213ORCID,Rossing Peter1415ORCID,Tankova Tsvetalina16ORCID,Tsapas Apostolos1718ORCID,Buse John B.19ORCID

Affiliation:

1. 1Leicester Diabetes Research Centre, University of Leicester, Leicester, U.K.

2. 2Leicester National Institute for Health Research Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Leicester, U.K.

3. 3Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

4. 4National Heart, Lung, and Blood Institute, Bethesda, MD

5. 5American Diabetes Association, Arlington, VA

6. 6Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC

7. 7Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD

8. 8Kidney and Hypertension Unit, Joslin Diabetes Center, Harvard Medical School, Boston, MA

9. 9Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

10. 10Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium

11. 11Università Cattolica del Sacro Cuore, Rome, Italy

12. 12Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

13. 13Division of Diabetes and Nutritional Sciences, School of Cardiovascular and Metabolic Medicine and Sciences, King’s College London, London, U.K.

14. 14Steno Diabetes Center Copenhagen, Herlev, Denmark

15. 15Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

16. 16Department of Endocrinology, Medical University—Sofia, Sofia, Bulgaria

17. 17Diabetes Centre, Clinical Research and Evidence-Based Medicine Unit, Aristotle University Thessaloniki, Thessaloniki, Greece

18. 18Harris Manchester College, University of Oxford, Oxford, U.K.

19. 19University of North Carolina School of Medicine, Chapel Hill, NC

Abstract

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the previous consensus statements on the management of hyperglycemia in type 2 diabetes in adults, published since 2006 and last updated in 2019. The target audience is the full spectrum of the professional health care team providing diabetes care in the U.S. and Europe. A systematic examination of publications since 2018 informed new recommendations. These include additional focus on social determinants of health, the health care system, and physical activity behaviors, including sleep. There is a greater emphasis on weight management as part of the holistic approach to diabetes management. The results of cardiovascular and kidney outcomes trials involving sodium–glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists, including assessment of subgroups, inform broader recommendations for cardiorenal protection in people with diabetes at high risk of cardiorenal disease. After a summary listing of consensus recommendations, practical tips for implementation are provided.

Funder

European Association for the Study of Diabetes

American Diabetes Association

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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