Affiliation:
1. Department of Pediatrics, University of Milan Milan, Italy
Abstract
The concentration of immunoreactive insulin in plasma has been determined following administration of tolbutamide and glucagon in seven children with newly diagnosed diabetic ketoacidosis. The basal plasma insulin levels were low, notwithstanding concomitantly high blood glucose levels. The plasma insulin concentration was increased by glucagon but not tolbutamide stimulation. These data suggest that a different mechanism of insulin release is induced by tolbutamide and glucagon.
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
29 articles.
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