Effects of a Tailored Text Messaging Intervention Among Diverse Adults With Type 2 Diabetes: Evidence From the 15-Month REACH Randomized Controlled Trial

Author:

Nelson Lyndsay A.12,Greevy Robert A.3,Spieker Andrew3,Wallston Kenneth A.4,Elasy Tom A.15,Kripalani Sunil1,Gentry Chad6,Bergner Erin M.12,LeStourgeon Lauren M.12,Williamson Sarah E.12,Mayberry Lindsay S.1257ORCID

Affiliation:

1. Department of Medicine, Vanderbilt University Medical Center, Nashville, TN

2. Center for Health Behavior and Health Education, Vanderbilt University Medical Center, Nashville, TN

3. Department of Biostatistics, Vanderbilt University, Nashville, TN

4. Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN

5. Center for Diabetes Translation Research, Vanderbilt University Medical Center, Nashville, TN

6. Department of Pharmacy, College of Pharmacy and Health Sciences, Lipscomb University, Nashville, TN

7. Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN

Abstract

OBJECTIVE Text messaging interventions have high potential for scalability and for reductions in health disparities. However, more rigorous, long-term trials are needed. We examined the long-term efficacy and mechanisms of a tailored text messaging intervention. RESEARCH DESIGN AND METHODS Adults with type 2 diabetes participated in a parallel-groups, 15-month randomized controlled trial and were assigned to receive Rapid Education/Encouragement and Communications for Health (REACH) for 12 months or control. REACH included interactive texts and tailored texts addressing medication adherence and nontailored texts supporting other self-care behaviors. Outcomes included hemoglobin A1c (HbA1c), diabetes medication adherence, self-care, and self-efficacy. RESULTS Participants (N = 506) were approximately half racial/ethnic minorities, and half were underinsured, had annual household incomes <$35,000, and had a high school education or less; 11% were homeless. Average baseline HbA1c was 8.6% ± 1.8%; 70.0 ± 19.7 mmol/mol) with n = 219 having HbA1c ≥8.5% (69 mmol/mol). Half were prescribed insulin. Retention was over 90%. Median response rate to interactive texts was 91% (interquartile range 75%, 97%). The treatment effect on HbA1c at 6 months (−0.31%; 95% CI −0.61%, −0.02%) was greater among those with baseline HbA1c ≥8.5% (−0.74%; 95% CI −1.26%, −0.23%), and there was no evidence of effect modification by race/ethnicity or socioeconomic disadvantage. REACH improved medication adherence and diet through 12 months and self-efficacy through 6 months. Treatment effects were not significant for any outcome at 15 months. REACH reduced barriers to adherence, but barrier reduction did not mediate outcome improvements. CONCLUSIONS REACH engaged at-risk patients in diabetes self-management and improved short-term HbA1c. More than texts alone may be needed to sustain the effects.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Heart, Lung, and Blood Institute

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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