Blockade of β1 Integrin–Laminin-5 Interaction Affects Spreading and Insulin Secretion of Rat β-Cells Attached on Extracellular Matrix
Author:
Affiliation:
1. Department of Genetic Medicine and Development, University Medical Center, Geneva, Switzerland
2. Cell Isolation and Transplantation Center, Division of Surgical Research, Department of Surgery, University Hospital, Geneva, Switzerland
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/55/5/1413/658711/zdb00506001413.pdf
Reference49 articles.
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3. Kikkawa Y, Yu H, Genersch E, Sanzen N, Sekiguchi K, Fassler R, Campbell KP, Talts JF, Ekblom P: Laminin isoforms differentially regulate adhesion, spreading, proliferation, and ERK activation of beta1 integrin-null cells. Exp Cell Res 300: 94–108,2004
4. Carter WG, Ryan MC, Gahr PJ: Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes. Cell 65: 599–610,1991
5. Fassler R, Meyer M: Consequences of lack of beta 1 integrin gene expression in mice. Genes Dev 9: 1896–1908,1995
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