Obstructive Sleep Apnea Among Obese Patients With Type 2 Diabetes

Author:

Foster Gary D.1,Sanders Mark H.2,Millman Richard3,Zammit Gary4,Borradaile Kelley E.1,Newman Anne B.2,Wadden Thomas A.5,Kelley David2,Wing Rena R.3,Pi Sunyer F. Xavier6,Darcey Valerie5,Kuna Samuel T.5,

Affiliation:

1. Temple University, Philadelphia, Pennsylvania;

2. University of Pittsburgh, Pittsburgh, Pennsylvania;

3. Brown University, Providence, Rhode Island;

4. Clinilabs, New York, New York;

5. University of Pennsylvania, Philadelphia, Pennsylvania;

6. Columbia University, New York, New York.

Abstract

OBJECTIVE To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Unattended polysomnography was performed in 306 participants. RESULTS Over 86% of participants had OSA with an apnea-hypopnea index (AHI) ≥5 events/h. The mean AHI was 20.5 ± 16.8 events/h. A total of 30.5% of the participants had moderate OSA (15 ≤ AHI <30), and 22.6% had severe OSA (AHI ≥30). Waist circumference (odds ratio 1.1; 95% CI 1.0–1.1; P = 0.03) was significantly related to the presence of OSA. Severe OSA was most likely in individuals with a higher BMI (odds ratio 1.1; 95% CI 1.0–1.2; P = 0.03). CONCLUSIONS Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among individuals with higher waist circumference and BMI.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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