Crystal Structure of the Major Diabetes Autoantigen Insulinoma-Associated Protein 2 Reveals Distinctive Immune Epitopes
Author:
Affiliation:
1. From the Systemic Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, Korea
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/56/1/41/383885/zdb00107000041.pdf
Reference48 articles.
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2. Atkinson MA, Eisenbarth GS: Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358:221–229,2001
3. Leslie RDG, Atkinson MA, Notkins AL: Autoantigens IA2 and GAD in type 1 (insulin dependent) diabetes. Diabetologia 42:3–14,1999
4. Nishino M, Ikegami H, Kawaguchi Y, Fujisawa T, Kawabata Y, Shintani M, Ono M, Horiki M, Kawasaki E, Ogihara T: Polymorphism in gene for islet autoantigen IA-2, and type 1 diabetes in Japanese subjects. Hum Immunol 62:518–522,2001
5. Notkins AL, Lernmark A: Autoimmune type 1 diabetes: resolved and unresolved issues. J Clin Imvest 108:1247–1252,2001
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