SIRT1 Takes a Backseat to AMPK in the Regulation of Insulin Sensitivity by Resveratrol
Author:
Affiliation:
1. From the Department of Medicine, McMaster University, Ontario, Canada.
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/59/3/551/663049/zdb00310000551.pdf
Reference23 articles.
1. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan;Howitz;Nature,2003
2. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae;Lin;Science,2000
3. Resveratrol improves health and survival of mice on a high-calorie diet;Baur;Nature,2006
4. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha;Lagouge;Cell,2006
5. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span;Pearson;Cell Metab,2008
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