1. Sunnybrook and Women’s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
2. Department of Medicine, University of Toronto, Toronto, Ontario, Canada
3. Department of Immunology, University of Toronto, Toronto, Ontario, Canada
4. the Welcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.
5. Program in Genetics and Genomics Biology, Hospital for Sick Children, Toronto, Ontario, Canada