Estrogen Can Prevent or Reverse Obesity and Diabetes in Mice Expressing Human Islet Amyloid Polypeptide
Author:
Affiliation:
1. Yale University, New Haven, Connecticut
2. University of Alberta, Edmonton, Canada
3. Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/51/7/2158/340788/db0702002158.pdf
Reference55 articles.
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3. Clark A, Charge SB, Badman MK, de Koning EJ: Islet amyloid in type 2 (non-insulin-dependent) diabetes. APMIS 104:12–18, 1996
4. Kahn SE, Andrikopoulos S, Verchere CB: Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes. Diabetes 48:241–253, 1999
5. Hoppener JW, Verbeek JS, de Koning EJ, Oosterwijk C, van Hulst KL, Visser-Vernooy HJ, Hofhuis FM, van Gaalen S, Berends MJ, Hackeng WH, et al.: Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice: lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia. Diabetologia 36:1258–1265, 1993
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