Effect of Intensive Insulin Therapy Using a Closed-Loop Glycemic Control System in Hepatic Resection Patients-Reference-Cited by-同舟云学术

Effect of Intensive Insulin Therapy Using a Closed-Loop Glycemic Control System in Hepatic Resection Patients

Published:2009-05-12 Issue:8 Volume:32 Page:1425-1427
ISSN:0149-5992
Container-title:Diabetes Care
language:en
Short-container-title:

Author:

Okabayashi Takehiro¹,Nishimori Isao²,Maeda Hiromichi¹,Yamashita Koichi³,Yatabe Tomoaki³,Hanazaki Kazuhiro¹

Affiliation:

1. Department of Surgery, Kochi Medical School, Kochi, Japan;

2. Department of Gastroenterology and Hepatology, Kochi Medical School, Kochi, Japan;

3. Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kochi, Japan.

Abstract

OBJECTIVE Intensive insulin therapy (IIT) reduces morbidity and mortality in patients in surgical intensive care units. The aim of this study is to assess the effect of IIT using a closed-loop system in hepatectomized patients. RESEARCH DESIGN AND METHODS Patients were randomly assigned to receive IIT using a closed-loop system: an artificial pancreas (AP group) or conventional insulin therapy using the sliding-scale method (SS group). RESULTS The incidence of surgical-site infection in the AP group was significantly lower than that in the SS group. The length of hospitalization required for patients in the AP group was significantly shorter than that in the SS group. CONCLUSIONS Total hospital costs for patients in the AP group were significantly lower than for patients in the SS group. IIT using a closed-loop system maintained near-normoglycemia and contributed to a reduction in the incidence of SSI and total hospital costs due to shortened hospitalization.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://diabetesjournals.org/care/article-pdf/32/8/1425/603792/zdc00809001425.pdf

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