Effects of Weight Loss Among Metabolically Healthy Obese Men and Women-Reference-Cited by-同舟云学术

Effects of Weight Loss Among Metabolically Healthy Obese Men and Women

Published:2010-06-23 Issue:9 Volume:33 Page:1957-1959
ISSN:0149-5992
Container-title:Diabetes Care
language:en
Short-container-title:

Author:

Janiszewski Peter M.¹,Ross Robert¹²

Affiliation:

1. School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada;

2. School of Medicine, Division of Endocrinology and Metabolism, Queen's University, Kingston, Ontario, Canada.

Abstract

OBJECTIVE Weight loss among metabolically healthy obese (MHO) individuals may be unnecessary or result in elevated cardio-metabolic risk. We studied the effects of exercise- or diet-induced weight loss on cardio-metabolic risk among MHO and metabolically abnormal obese (MAO) adults. RESEARCH DESIGN AND METHODS Participants were 63 MHO and 43 MAO adults who took part in 3 to 6 months of exercise- or diet-induced weight loss intervention. Changes in anthropometry, adipose tissue distribution, and cardio-metabolic risk factors were assessed. RESULTS Body weight, waist circumference, and total abdominal and visceral adipose tissue were reduced in all subjects (P < 0.05). Improvements in insulin sensitivity were observed in MHO and MAO men and women (P < 0.05), but were greater in the MAO individuals (P < 0.05). Fasting insulin was the only other cardio-metabolic improvement among MHO individuals (P < 0.05). CONCLUSIONS Lifestyle-induced weight loss among MHO subjects is associated with a reduction in total and abdominal obesity and improvement in selected cardio-metabolic risk factors.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://diabetesjournals.org/care/article-pdf/33/9/1957/607471/zdc00910001957.pdf

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