Cotton-wool Spots in Diabetic Retinopathy

Author:

Kohner Eva M1,Dollery C T1,Bulpitt C J1

Affiliation:

1. Royal Postgraduate Medical School Ducane Road, London W. 12, U.K.

Abstract

In nineteen patients with diabetic retinopathy the appearance and life history of cotton-wool spots were studied by serial color photographs and fluorescence angiograms. Cotton-wool spots are a feature of both mild and severe diabetic retinopathy but, while their appearance is similar to that in hypertension, the associated capillary abnormalities are more severe. On fluorescence angiograms cottonwool spots are associated with arteriolar occlusion with an area of capillary closure and are surrounded by abnormal dilated capillaries. Capillary abnormalities precede the development of arteriolar occlusion which is necessary for the development of cotton-wool spots. Cotton-wool spots persist for long periods. Their mean half-life is 8.1 months in patients under forty years of age and 17.2 months in patients over the age of forty. Even when cotton-wool spots disappear, capillary closure persists. Following yttrium90 implantation of the pituitary gland the half-life of cotton-wool spots was 2.3 months.

Publisher

American Diabetes Association

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3