1. Department of Medicine, University of Eastern Finland, Kuopio, Finland
2. Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
3. Department of Medicine and Department of Clinical Nutrition, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
4. Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland
5. Nuclear Magnetic Resonance Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland
6. Department of Human Genetics, Department of Microbiology, Immunology, and Molecular Genetics, and Department of Medicine, University of California, Los Angeles, Los Angeles, California
7. Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
8. National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland
9. Department of Genetics, University of North Carolina, Chapel Hill, North Carolina
10. Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan
11. School of Social and Community Medicine, University of Bristol, Bristol, U.K.
12. Unit of General Practice, Oulu University Hospital, Oulu, Finland.