Effect of Guar Gum on 24-hour Insulin Requirements of Insulin-dependent Diabetic Subjects as Assessed by an Artificial Pancreas

Author:

Christiansen J Sandahl1,Bonnevie-Nielsen V1,Svendsen P Aaby1,Rubin P1,Rønn B1,Nerup J1

Affiliation:

1. Steno Memorial Hospital Copenhagen, Denmark

Abstract

The effect of guar gum on insulin requirements, mean blood glucose (MBG), and mean amplitude of glycemic excursions (MAGE) was investigated in seven insulin-dependent diabetic subjects without endogenous insulin secretion by means of an artificial pancreas (Biostator). Fifty-four hours after the withdrawal of long-acting insulin, the patients were controlled for two consecutive days by the artificial pancreas, under standardized and identical conditions, except for the ingestion of guar gum before meals on the second day. The 24-h insulin requirements were significantly reduced by 12.4% on the day with guar gum (P < 0.05). No statistically significant effects were observed on MBG and MAGE.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Guar Gum;Handbook of Dietary Fiber;2001-08-17

2. Treatment of Diabetes with High-Fiber Diets;CRC Handbook of Dietary Fiber in Human Nutrition, Third Edition;2001-06-27

3. Dietary Fiber Intakes and Insulin Requirements Pregnant Women with Type 1 Diabetes;Journal of the American Dietetic Association;2001-03

4. Metabolic advantages of spreading the nutrient load: effects of increased meal frequency in non-insulin-dependent diabetes;The American Journal of Clinical Nutrition;1992-02-01

5. No effects of high-fiber diets on metabolic control and insulin-sensitivity in type 1 diabetic subjects;Diabetes Research and Clinical Practice;1991-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3