Population-Based Incidence of IDDM in the State of São Paulo, Brazil

Abstract

OBJECTIVE To study the incidence of IDDM among children, infants to 14 yr of age, in the state of São Paulo, Brazil, 1987–1991. RESEARCH DESIGN AND METHODS A prospective population-based register was established, using physician reports of newly diagnosed IDDM patients < 15 yr of age as the primary source of case identification and school surveys as the main secondary source. Data were collected according to the methods recommended by the Diabetes Epidemiology Research International group. RESULTS Case ascertainment was estimated at 95.0, 92.8, and 98.8% complete for each of the three cities studied. The average annual IDDM incidence was 7.6/100,000 inhabitants (95% confidence interval, 5.6–9.7). We found a higher incidence rate in girls than boys. CONCLUSIONS The incidence of childhood IDDM in a tropical region in South America (São Paulo, Brazil) is in the middle incidence range observed in developed countries throughout the world. Increased incidence of IDDM in girls compared with boys will be tested by the ongoing Brazilian incidence study being developed in 18 other centers across the country.