Hyperglycemic Crises in Adults With Diabetes: A Consensus Report

Author:

Umpierrez Guillermo E.1ORCID,Davis Georgia M.1ORCID,ElSayed Nuha A.23ORCID,Fadini Gian Paolo45ORCID,Galindo Rodolfo J.6ORCID,Hirsch Irl B.7ORCID,Klonoff David C.8ORCID,McCoy Rozalina G.910ORCID,Misra Shivani1112ORCID,Gabbay Robert A.23ORCID,Bannuru Raveendhara R.2ORCID,Dhatariya Ketan K.1314ORCID

Affiliation:

1. 1Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA

2. 2American Diabetes Association, Arlington, VA

3. 3Department of Medicine, Harvard Medical School, Boston, MA

4. 4Department of Medicine, University of Padua, Padua, Italy

5. 5Veneto Institute of Molecular Medicine, Padua, Italy

6. 6Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL

7. 7Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, WA

8. 8Diabetes Research Institute, Mills-Peninsula Medical Center, San Mateo, CA

9. 9Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD

10. 10University of Maryland Institute for Health Computing, Bethesda, MD

11. 11Division of Metabolism, Digestion & Reproduction, Imperial College London, U.K.

12. 12Department of Diabetes & Endocrinology, Imperial College Healthcare NHS Trust, London, U.K.

13. 13Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, U.K.

14. 14Department of Medicine, Norwich Medical School, University of East Anglia, Norwich, U.K.

Abstract

The American Diabetes Association (ADA), European Association for the Study of Diabetes (EASD), Joint British Diabetes Societies for Inpatient Care (JBDS), American Association of Clinical Endocrinology (AACE), and Diabetes Technology Society (DTS) convened a panel of internists and diabetologists to update the ADA consensus statement on hyperglycemic crises in adults with diabetes, published in 2001 and last updated in 2009. The objective of this consensus report is to provide up-to-date knowledge about the epidemiology, pathophysiology, clinical presentation, and recommendations for the diagnosis, treatment, and prevention of diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) in adults. A systematic examination of publications since 2009 informed new recommendations. The target audience is the full spectrum of diabetes health care professionals and individuals with diabetes.

Funder

NIH

Publisher

American Diabetes Association

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