Painful Diabetic Neuropathy: A Management-Centered Review

Abstract

IN BRIEF Painful diabetic neuropathy is a common complication of diabetes and can affect many aspects of life and severely limit patients' daily functions. This article reviews the diagnosis, prevention, and management of painful diabetic neuropathy. This condition can be difficult to treat, which frustrates both providers and patients. Commonly used agents, including the recently approved duloxetine and pregabalin, are reviewed, and their effective dose ranges,titration schemes, contraindications, and recommended monitoring are discussed.