Reduced Incidence of Lower-Extremity Amputations in People With Diabetes in Scotland

Author:

Kennon Brian1,Leese Graham P.2,Cochrane Lynda3,Colhoun Helen4,Wild Sarah5,Stang Duncan6,Sattar Naveed7,Pearson Donald8,Lindsay Robert S.9,Morris Andrew D.10,Livingstone Shona11,Young Matthew12,McKnight John13,Cunningham Scott14

Affiliation:

1. Diabetes & Endocrinology Department, Southern General Hospital, Glasgow, U.K.

2. Diabetes & Endocrinology Department, Ninewells Hospital, Dundee, Tayside, U.K.

3. Division of Clinical and Population Sciences and Education, Dundee, Tayside, U.K.

4. Public Health Wellcome Trust Centre for Molecular Medicine Clinical Research Centre, University of Dundee, Dundee, Tayside, U.K.

5. Public Health, University of Edinburgh, Lothian, U.K.

6. Podiatry Department, Hairmyres Hospital, East Kilbride, Lanarkshire, U.K.

7. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Strathclyde, U.K.

8. University of Aberdeen, Diabetes King’s College, Aberdeen, Grampian, U.K.

9. British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Strathclyde, U.K.

10. Biomedical Research Institute, University of Dundee, Tayside, U.K.

11. Statistics Department, Wellcome Trust Centre for Molecular Medicine Clinical Research Centre, University of Dundee, Tayside, U.K.

12. Royal Infirmary of Edinburgh, Diabetes Centre, Edinburgh, Lothian, U.K.

13. Western General Hospital, Diabetes Centre, Edinburgh, Lothian, U.K.

14. SCI Diabetes Collaboration Ninewells Hospital and Medical School, University of Dundee Clinical Technology Centre, Dundee, Tayside, U.K.

Abstract

OBJECTIVE To establish the incidence of nontraumatic lower-extremity amputation (LEA) in people with diabetes in Scotland. RESEARCH DESIGN AND METHODS This cohort study linked national morbidity records and diabetes datasets to establish the number of people with diabetes who underwent nontraumatic major and minor LEA in Scotland from 2004 to 2008. RESULTS Two thousand three hundred eighty-two individuals with diabetes underwent a nontraumatic LEA between 2004 and 2008; 57.1% (n = 1,359) underwent major LEAs. The incidence of any LEA among persons with diabetes fell over the 5-year study period by 29.8% (3.04 per 1,000 in 2004 to 2.13 per 1,000 in 2008, P < 0.001). Major LEA rates decreased by 40.7% from 1.87 per 1,000 in 2004 to 1.11 per 1,000 in 2008 (P < 0.001). CONCLUSIONS There has been a significant reduction in the incidence of LEA in persons with diabetes in Scotland between 2004 and 2008, principally explained by a reduction in major amputation.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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