Affiliation:
1. Departments of Medicine, University of Southern California School of Medicine and the Los Angeles County Hospital Los Angeles, California
Abstract
A thirty-eight-year-old female diabetic is described who bears symmetrical lipomas at the sites of insulin injection, which have persisted for twenty-six years. Incubation of biopsy specimens of adipose tissue from one of the lipomas compared with that of adjacent normal subcutaneous adipose tissue revealed an increase in baseline rates of oxidation of both glucose-1 and glucose-6-C-14 to C-14-02 by the lipoma tissue, as well as greater incorporation of C-14 into fatty acids. These parameters were not influenced by added insulin in the normal tissue, but were greatly stimulated in lipoma tissue. The lipoma tissue was clearly converting labeled glucose to fatty acid more efficiently than the normal tissue.
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献