2021年度中国消化病领域高价值论文TOP100
以往我们对一篇论文的价值评估,是通过期刊影响因子或被引频次来判断,这种采用单一指标评判论文的学术价值因有失偏颇而广受诟病。北京同舟云网络信息技术有限公司创立了一种优选算法,综合考虑Metrics 期刊评分、论文被引频次、文献类型以及论文发表时间等多种因素,对每篇论文进行深度解析与计算,并赋予分值,以量化每篇论文的学术价值和影响力。本推荐表是在系统全面准确地统计中国机构作者发表的消化病领域国际论文的基础上(说明:消化病领域专家为主要完成人发表的全部论文均入选,不再筛选论文的内容主题),对每篇论文依上述方法进行计算并赋分排名而得出的,供相关学者学习、评判、参考和借鉴。
序号 | 年份 | 标题 | 期刊 | 主要完成人 | 论文评分 | 1 | 2021 | Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study | CLIN MICROBIOL INFEC | 董卫国,武汉大学,人民医院,消化内科; | 10546.72 | 2 | 2021 | Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice | NAT GENET | 黄瑛,复旦大学上海医学院,儿科医院,消化科; | 6777.76 | 3 | 2021 | Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites | GUT | 于君,香港中文大学,内科及药物治疗学系; | 6371.04 | 4 | 2021 | The Neutrophil-to-Lymphocyte Ratio Determines Clinical Efficacy of Corticosteroid Therapy in Patients with COVID-19 | CELL METAB | 张鑫,武汉大学; | 6082.4 | 5 | 2021 | Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial | SIGNAL TRANSDUCT TAR | 谢渭芬,海军军医大学,附属长征医院,消化内科; | 5806.88 | 6 | 2021 | Potential intestinal infection and faecal-oral transmission of SARS-CoV-2 | NAT REV GASTRO HEPAT | 朱书,中国科学技术大学,生命科学与医学部; | 5607.68 | 7 | 2021 | Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing | ADV SCI | 王辉,中山大学,附属第六医院; | 5344.64 | 8 | 2021 | SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs | CELL RES | 汪芳裕,东部战区总医院,,消化内科; | 5073.12 | 9 | 2021 | Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncology | BRIEF BIOINFORM | 戴世学,广东省人民医院,,消化内科; | 4987.2 | 10 | 2021 | The Role of Angiotensin Converting Enzyme 2 in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection | GASTROENTEROLOGY | 沈祖尧,香港中文大学; | 4411.68 | 11 | 2021 | F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer | GUT | 房静远,上海交通大学医学院,仁济医院,消化内科; | 4387.04 | 12 | 2021 | Clinical Features of Patients Infected With Coronavirus Disease 2019 With Elevated Liver Biochemistries: A Multicenter, Retrospective Study | HEPATOLOGY | 晏维,华中科技大学,附属同济医院,消化内科; | 4379.36 | 13 | 2021 | Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease | IMMUNITY | 靳津,浙江大学,生命科学研究院; | 4067.36 | 14 | 2021 | Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies | GUT | 张常华,中山大学,附属第一医院; | 4003.04 | 15 | 2021 | Regulatory T-cell and neutrophil extracellular trap interaction contributes to carcinogenesis in non-alcoholic steatohepatitis | J HEPATOL | 田德安,华中科技大学,附属同济医院,消化内科; | 3997.12 | 16 | 2021 | Population-Level Configurations of Gut Mycobiome Across 6 Ethnicities in Urban and Rural China | GASTROENTEROLOGY | 缪应雷,昆明医科大学,第一附属医院,消化内科; | 3963.68 | 17 | 2021 | GCdiscrimination: identification of gastric cancer based on a milliliter of blood | BRIEF BIOINFORM | 张德奎,兰州大学,第二医院,消化科; | 3963.2 | 18 | 2021 | Enterotoxigenic Bacteroides fragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p | GASTROENTEROLOGY | 洪洁,上海交通大学医学院,仁济医院,消化科; | 3771.68 | 19 | 2021 | Microbial Community Heterogeneity Within Colorectal Neoplasia and its Correlation With Colorectal Carcinogenesis | GASTROENTEROLOGY | 于君,香港中文大学,内科及药物治疗学系; | 3771.68 | 20 | 2021 | AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1 | NAT CELL BIOL | 林舒勇,厦门大学,生命科学学院; | 3767.04 | 21 | 2021 | Development and Validation of a Novel Computed-Tomography Enterography Radiomic Approach for Characterization of Intestinal Fibrosis in Crohn's Disease | GASTROENTEROLOGY | 毛仁,中山大学,附属第一医院,消化内科; | 3707.68 | 22 | 2021 | Alterations in the Gut Virome in Obesity and Type 2 Diabetes Mellitus | GASTROENTEROLOGY | 缪应雷,昆明医科大学,第一附属医院,消化内科; | 3643.68 | 23 | 2021 | Bio-Multifunctional Hydrogel Patches for Repairing Full-Thickness Abdominal Wall Defect | ADV FUNCT MATER | 胡继霖,青岛大学,附属医院; | 3525.76 | 24 | 2021 | Regular Use of Proton Pump Inhibitor and the Risk of Inflammatory Bowel Disease: Pooled Analysis of 3 Prospective Cohorts | GASTROENTEROLOGY | 张常华,中山大学,附属第一医院; | 3451.68 | 25 | 2021 | Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer | ADV SCI | 徐雷鸣,上海交通大学医学院,新华医院,内窥镜诊治部; | 3424.64 | 26 | 2021 | Tumor heterogeneity in autophagy-dependent ferroptosis | AUTOPHAGY | 王晓艳,中南大学,湘雅三医院,消化内科; | 3398.72 | 27 | 2021 | LINC00941promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-beta/SMAD2/3 signaling pathway | CELL DEATH DIFFER | 许冰,空军军医大学,西京消化病医院; | 3378.72 | 28 | 2021 | Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis | GUT | 唐茹琦,上海交通大学医学院,仁济医院,消化科; | 3363.04 | 29 | 2021 | Novel scheme for non-invasive gut bioinformation acquisition with a magnetically controlled sampling capsule endoscope | GUT | 蔺蓉,华中科技大学,同济医学院,消化内科; | 3363.04 | 30 | 2021 | SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function | MOL CELL | 王正廷,上海交通大学医学院,瑞金医院,消化内科; | 3359.2 | 31 | 2021 | NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis | CELL RES | 周天华,浙江大学,医学院基础医学系; | 3345.12 | 32 | 2021 | Gut microbiome, liver immunology, and liver diseases | CELL MOL IMMUNOL | 马雄,上海交通大学医学院,仁济医院,消化科; | 3341.44 | 33 | 2021 | Timing of endoscopy for acute upper gastrointestinal bleeding: a territory-wide cohort study | GUT | 沈祖尧,香港中文大学; | 3235.04 | 34 | 2021 | Endoscopic Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration for Prevention of Gastric Variceal Bleeding: A Randomized Controlled Trial | HEPATOLOGY | 杨丽,四川大学,华西医院,消化科; | 3227.36 | 35 | 2021 | Therapeutic resistance of pancreatic cancer: Roadmap to its reversal | BBA-REV CANCER | 谢克平,华南理工大学; | 3219.2 | 36 | 2021 | Risk factors for depression and anxiety in healthcare workers deployed during the COVID-19 outbreak in China | SOC PSYCH PSYCH EPID | 侯晓华,华中科技大学,附属协和医院,消化内科; | 3157.6 | 37 | 2021 | In situ growth of nano-antioxidants on cellular vesicles for efficient reactive oxygen species elimination in acute inflammatory diseases | NANO TODAY | 施敏,上海交通大学医学院,同仁医院,消化内科; | 3077.12 | 38 | 2021 | Systematic review: the global incidence of faecal microbiota transplantation-related adverse events from 2000 to 2020 | ALIMENT PHARM THER | 张发明,南京医科大学,第二附属医院,消化科; | 3028.96 | 39 | 2021 | PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation | AUTOPHAGY | 陈烨,南方医科大学,南方医院,消化内科; | 3014.72 | 40 | 2021 | Gut mycobiome: A promising target for colorectal cancer | BBA-REV CANCER | 曹海龙,天津医科大学,总医院,消化内科; | 2963.2 | 41 | 2021 | Gold-Doped Covalent-Organic Framework Reveals Specific Serum Metabolic Fingerprints as Point of Crohn's Disease Diagnosis | ADV FUNCT MATER | 吴昊,复旦大学上海医学院,中山医院,消化科; | 2949.76 | 42 | 2021 | Colonic mucus-accumulating tungsten oxide nanoparticles improve the colitis therapy by targeting Enterobacteriaceae | NANO TODAY | 陈汉清,华南理工大学 附属第二医院 消化内科; | 2949.12 | 43 | 2021 | Advanced nanomaterials as sample technique for bio-analysis | TRAC-TREND ANAL CHEM | 沈锡中,复旦大学上海医学院,中山医院,消化科; | 2912.16 | 44 | 2021 | Micropeptide ASAP encoded by LINC00467 promotes colorectal cancer progression by directly modulating ATP synthase activity | J CLIN INVEST | 王良静,浙江大学,附属第二医院,消化内科; | 2898.4 | 45 | 2021 | Risk Stratification Based on Chronic Liver Failure Consortium Acute Decompensation Score in Patients With Child-Pugh B Cirrhosis and Acute Variceal Bleeding | HEPATOLOGY | 韩国宏,空军军医大学,西京医院,消化介入科; | 2843.36 | 46 | 2021 | Risk SNP-induced lncRNA-SLCC1 drives colorectal cancer through activating glycolysis signaling | SIGNAL TRANSDUCT TAR | 房静远,上海交通大学医学院,仁济医院,消化内科; | 2798.88 | 47 | 2021 | Longitudinal dynamics of gut bacteriome, mycobiome and virome after fecal microbiota transplantation in graft-versus-host disease | NAT COMMUN | 黃秀娟,香港中文大学,内科及药物治疗学系; | 2744.48 | 48 | 2021 | SARS-CoV-2-specific immune response in COVID-19 convalescent individuals | SIGNAL TRANSDUCT TAR | 林军,武汉大学,第二临床学院消化内科; | 2734.88 | 49 | 2021 | ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells | J CLIN INVEST | 王正廷,上海交通大学医学院,瑞金医院,消化内科; | 2706.4 | 50 | 2021 | Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells | ADV FUNCT MATER | 徐灿,第二军医大学,长海医院,消化科; | 2693.76 | 51 | 2021 | The Evolution Pathway of Ammonia-Oxidizing Archaea Shaped by Major Geological Events | MOL BIOL EVOL | 曹志伟,同济大学,生命科学与技术学院; | 2687.52 | 52 | 2021 | Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora | ADV SCI | 王正廷,上海交通大学医学院,瑞金医院,消化内科; | 2656.64 | 53 | 2021 | lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/beta-Catenin Pathway and Oncogenic Autophagy | MOL THER | 施敏,上海交通大学医学院,同仁医院,消化内科; | 2653.76 | 54 | 2021 | IL-1 beta-Induced Elevation of Solute Carrier Family 7 Member 11 Promotes Hepatocellular Carcinoma Metastasis Through Up-regulating Programmed Death Ligand 1 and Colony-Stimulating Factor 1 | HEPATOLOGY | 夏丽敏,空军军医大学,西京医院,消化内科; | 2651.36 | 55 | 2021 | The Clinical Significance of Hepatic CD69(+)CD 103(+)CD 8(+) Resident-Memory T Cells in Autoimmune Hepatitis | HEPATOLOGY | 马雄,上海交通大学医学院,仁济医院,消化科; | 2651.36 | 56 | 2021 | The Clinical Significance of Hepatic CD69(+)CD103(+)CD8(+) Resident-Memory T Cells in Autoimmune Hepatitis | HEPATOLOGY | 马雄,上海交通大学医学院,仁济医院,消化科; | 2651.36 | 57 | 2021 | The Relationship Between Diabetes Mellitus and COVID-19 Prognosis: A Retrospective Cohort Study in Wuhan, China | AM J MED | 林军,武汉大学,第二临床学院消化内科; | 2640.96 | 58 | 2021 | ELNet:Automatic classification and segmentation for esophageal lesions using convolutional neural network | MED IMAGE ANAL | 何晓璞,南京医科大学,第一附属医院,老年医学科(消化); | 2615.68 | 59 | 2021 | BFAR coordinates TGF beta signaling to modulate Th9-mediated cancer immunotherapy | J EXP MED | 温珍珍,附属邵逸夫医院 消化内科; | 2605.12 | 60 | 2021 | The intratumoural microbiota in cancer: new insights from inside | BBA-REV CANCER | 曹海龙,天津医科大学,总医院,消化内科; | 2579.2 | 61 | 2021 | Identification of microbial markers across populations in early detection of colorectal cancer | NAT COMMUN | 朱瑞新,同济大学,生命科学与技术学院; | 2552.48 | 62 | 2021 | Injectable Self-Healing Adhesive pH-Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing | NANO-MICRO LETT | 郭保林,西安交通大学,前沿科学技术研究院; | 2538.24 | 63 | 2021 | Inhibition of the PLK1-Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer | ADV SCI | 吴小剑,中山大学,附属第六医院; | 2528.64 | 64 | 2021 | Diarrhea and altered inflammatory cytokine pattern in severe coronavirus disease 2019: Impact on disease course and in-hospital mortality | J GASTROEN HEPATOL | 侯晓华,华中科技大学,附属协和医院,消化内科; | 2501.12 | 65 | 2021 | DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy | CELL DEATH DIFFER | 关新元,中山大学,肿瘤防治中心; | 2482.72 | 66 | 2021 | Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer | J IMMUNOTHER CANCER | 张艳桥,哈尔滨医科大学,附属肿瘤医院,消化内科; | 2482.08 | 67 | 2021 | Exogenous l-fucose protects the intestinal mucosal barrier depending on upregulation of FUT2-mediated fucosylation of intestinal epithelial cells | FASEB J | 蔺蓉,华中科技大学,同济医学院,消化内科; | 2468.64 | 68 | 2021 | Expression, regulation, and function of exosome-derived miRNAs in cancer progression and therapy | FASEB J | 孙明军,中国医科大学,附属第一医院,消化内科; | 2468.64 | 69 | 2021 | miR-30c inhibits angiogenesis by targeting delta-like ligand 4 in liver sinusoidal endothelial cell to attenuate liver fibrosis | FASEB J | 陆伦根,上海交通大学医学院,第一人民医院,消化科; | 2468.64 | 70 | 2021 | L-lactate promotes intestinal epithelial cell migration to inhibit colitis | FASEB J | 李延青,山东大学,齐鲁医院,消化内科; | 2468.64 | 71 | 2021 | Fluorofenidone protects liver against inflammation and fibrosis by blocking the activation of NF-kappa B pathway | FASEB J | 阳恵湘,中南大学,湘雅医院; | 2404.64 | 72 | 2021 | Novel approaches to intervene gut microbiota in the treatment of chronic liver diseases | FASEB J | 沈锡中,复旦大学上海医学院,中山医院,消化科; | 2404.64 | 73 | 2021 | Sex bias in alcohol research: A 20-year comparative study | FRONT NEUROENDOCRIN | 王菲,中山大学 附属第七医院 消化医学中心; | 2400 | 74 | 2021 | The role of natural killer cell in gastrointestinal cancer: killer or helper | ONCOGENE | 于君,香港中文大学,内科及药物治疗学系,; | 2393.44 | 75 | 2021 | A Sequential Algorithm Combining ADAPT and Liver Stiffness Can Stage Metabolic-Associated Fatty Liver Disease in Hospital-Based and Primary Care Patients | AM J GASTROENTEROL | 黄炜燊,香港中文大学,内科及药物治疗部消化疾病研究所,; | 2360.8 | 76 | 2021 | Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition | FASEB J | 言君凯,上海交通大学医学院,新华医院,儿消化营养; | 2340.64 | 77 | 2021 | Translation of noncoding RNAs and cancer | CANCER LETT | 肖煜峰,第三军医大学,新桥医院,消化内科; | 2329.6 | 78 | 2021 | APC(CDC20)-mediated degradation of PHD3 stabilizes HIF-1a and promotes tumorigenesis in hepatocellular carcinoma | CANCER LETT | 徐凌,上海交通大学医学院,同仁医院,消化内科; | 2329.6 | 79 | 2021 | Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial | LANCET GASTROENTEROL | 于红刚,武汉大学,人民医院,消化内科; | 2312.96 | 80 | 2021 | Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy | SCI ADV | 刘祥瑞,浙江大学,化学工程与生物工程学系生物工程研究所,; | 2290.56 | 81 | 2021 | Gut Microbiota in Cancer Immune Response and Immunotherapy | TRENDS CANCER | 房静远,上海交通大学医学院,仁济医院,消化内科; | 2286.88 | 82 | 2021 | Epigenetic silencing of miR-144/451a cluster contributes to HCC progression via paracrine HGF/MIF-mediated TAM remodeling | MOL CANCER | 刘雷,第四军医大学 唐都医院 消化内科; | 2284.64 | 83 | 2021 | Boosting Room Temperature Phosphorescence Performance by Alkyl Modification for Intravital Orthotopic Lung Tumor Imaging | SMALL | 汤琪云,南京医科大学,第一附属医院,老年医学科(消化); | 2281.44 | 84 | 2021 | Microbial and metabolic features associated with outcome of infliximab therapy in pediatric Crohn's disease | GUT MICROBES | 张婷,上海交通大学医学院,上海市儿童医院,消化科医师(普); | 2275.68 | 85 | 2021 | Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism | CANCER RES | 谢渭芬,海军军医大学,附属长征医院,消化内科; | 2260.32 | 86 | 2021 | 5 '-tRF-GlyGCC: a tRNA-derived small RNA as a novel biomarker for colorectal cancer diagnosis | GENOME MED | 刘焕亮,中山大学,附属第六医院; | 2253.76 | 87 | 2021 | YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect | CELL DEATH DIFFER | 孟祥军,上海交通大学医学院,第九人民医院,消化内科; | 2226.72 | 88 | 2021 | Aberrantly high activation of a FoxM1-STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers | SIGNAL TRANSDUCT TAR | 李纪鹏,第四军医大学,西京医院; | 2222.88 | 89 | 2021 | Circular RNAs' cap-independent translation protein and its roles in carcinomas | MOL CANCER | 王小艳,南京医科大学,第一附属医院,; | 2220.64 | 90 | 2021 | Fully automated magnetically controlled capsule endoscopy for examination of the stomach and small bowel: a prospective, feasibility, two-centre study | LANCET GASTROENTEROL | 谢霞,第三军医大学,新桥医院,消化内科; | 2184.96 | 91 | 2021 | Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration | MICROBIOME | 杨仕明,陆军军医大学,新桥医院,消化科; | 2177.12 | 92 | 2021 | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections | NAT COMMUN | 龚四堂,广州市妇女儿童医疗中心,消化科; | 2168.48 | 93 | 2021 | Use of artificial intelligence for detection of gastric lesions by magnetically controlled capsule endoscopy | GASTROINTEST ENDOSC | 廖专,海军军医大学,长海医院,消化内科; | 2138.72 | 94 | 2021 | Efficacy and safety of weekly paclitaxel with or without ramucirumab as second-line therapy for the treatment of advanced gastric or gastroesophageal junction adenocarcinoma (RAINBOW-Asia): a randomised multicentre, double-blind, phase 3 trial | LANCET GASTROENTEROL | 沈琳,北京大学,肿瘤医院,消化肿瘤内科; | 2120.96 | 95 | 2021 | Hepatitis Flare During Immunotherapy in Patients With Current or Past Hepatitis B Virus Infection | AM J GASTROENTEROL | 陈力元,香港中文大学; | 2104.8 | 96 | 2021 | Camrelizumab Combined with Chemotherapy Followed by Camrelizumab plus Apatinib as First-line Therapy for Advanced Gastric or Gastroesophageal Junction | CLIN CANCER RES | 沈琳,北京大学,肿瘤医院,消化肿瘤内科; | 2079.84 | 97 | 2021 | Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications | ONCOGENE | 黄子隽,香港中文大学,消化病研究所; | 2073.44 | 98 | 2021 | Evaluation of the effects of an artificial intelligence system on endoscopy quality and preliminary testing of its performance in detecting early gastric cancer: a randomized controlled trial | ENDOSCOPY | 于红刚,武汉大学,人民医院,消化内科; | 2070.56 | 99 | 2021 | FOXD1-AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway | MOL ONCOL | 施敏,上海交通大学医学院,同仁医院,消化内科; | 2032.16 | 100 | 2021 | M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/beta-Catenin Signalling Axis | J CROHNS COLITIS | 邓飞鸿,南方医科大学,南方医院,消化内科; 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