Trends in NMR Structural Elucidation Of Polycyclic Cages, Namely: Adamantane, Pentacycloundecane and Trishomocubane
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Published:2021
Issue:
Volume:75
Page:
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ISSN:0379-4350
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Container-title:South African Journal of Chemistry
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language:
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Short-container-title:S.Afr.j.chem.
Author:
Kelani Monsuru T.,Dieudonné Darcelle,Skowron Kornelia J.,Pedigo Clayton,Govender Thavenden,Kruger Hendrik G.,Naicker Tricia,Onajole Oluseye K.
Abstract
ABSTRACT Advances in Nuclear Magnetic Resonance (NMR) spectroscopy is a cornerstone in structure elucidation of polycyclic 'cage' scaffolds. Due to the compactness of these compounds, much overlap, as well as unique through-space and bond NMR interactions are frequently observed. This review serves as a guide for the NMR elucidation of future derivatives by providing some of the typical and relevant aspects of the characteristic trends, substituent patterns and chemical shift behaviour for the identification of the polycyclic structures, namely adamantane, pentacycloundecane and trishomocubane derivatives. Keywords: adamantane, NMR elucidation, pentacycloundecane, polycyclic compounds, trishomocubane
Publisher
Academy of Science of South Africa
Subject
General Chemistry