Affiliation:
1. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139
Abstract
A new model is used to analyze the fully coupled problem of pulsatile blood flow through a compliant, axisymmetric stenotic artery using the finite element method. The model uses large displacement and large strain theory for the solid, and the full Navier-Stokes equations for the fluid. The effect of increasing area reduction on fluid dynamic and structural stresses is presented. Results show that pressure drop, peak wall shear stress, and maximum principal stress in the lesion all increase dramatically as the area reduction in the stenosis is increased from 51 to 89 percent. Further reductions in stenosis cross-sectional area, however, produce relatively little additional change in these parameters due to a concomitant reduction in flow rate caused by the losses in the constriction. Inner wall hoop stretch amplitude just distal to the stenosis also increases with increasing stenosis severity, as downstream pressures are reduced to a physiological minimum. The contraction of the artery distal to the stenosis generates a significant compressive stress on the downstream shoulder of the lesion. Dynamic narrowing of the stenosis is also seen, further augmenting area constriction at times of peak flow. Pressure drop results are found to compare well to an experimentally based theoretical curve, despite the assumption of laminar flow.
Subject
Physiology (medical),Biomedical Engineering
Reference46 articles.
1. ADINA System User Manuals, 1997, User’s Guide (Report 97–1), Theory and Modeling Guides (Reports ARD 97–7 and 97–8), Verification Manual (Report ARD 97–9), ADINA R&D Inc.
2. Bathe, K. J., 1996, Finite Element Procedures, Prentice Hall, NJ.
3. Bathe, K. J., Zhang, H., and Shanhong, J., 1999, “Finite Element Analysis of Fluid Flows Fully Coupled With Structural Interactions,” Computers and Structures, in press.
4. Bathe
K. J.
, ZhangH., and WangM. H., 1995, “Finite Element Analysis of Incompressible and Compressible Fluid Flows With Free Surfaces and Structural Interactions,” Computers and Structures, Vol. 56, No. 2/3, pp. 193–213.
5. Bathe
K. J.
, ZhangH., and ZhangX., 1997, “Some Advances in the Analysis of Fluid Flows,” Computers and Structures, Vol. 64, No. 5/6, pp. 909–930.
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