A Novel Approach to Design Lesion-Specific Stents for Minimum Recoil-Reference-Cited by-同舟云学术

A Novel Approach to Design Lesion-Specific Stents for Minimum Recoil

Published:2016-12-21 Issue:1 Volume:11 Page:
ISSN:1932-6181
Container-title:Journal of Medical Devices
language:en
Short-container-title:

Author:

Farhan Khan Muhammad¹,Brackett David²,Ashcroft Ian³,Tuck Christopher³,Wildman Ricky⁴

Affiliation:

1. Mem. ASME Department of Mechanical, Materials and Manufacturing Engineering, Faculty of Engineering, University of Nottingham, University Park, Nottingham NG72RD, UK e-mail:

2. Department of Mechanical, Materials and Manufacturing Engineering, Faculty of Engineering, University of Nottingham, University Park, Nottingham NG72RD, UK e-mail:

3. Professor Department of Mechanical, Materials and Manufacturing Engineering, Faculty of Engineering, University of Nottingham, University Park, Nottingham NG72RD, UK e-mail:

4. Professor Department of Chemical and Environmental Engineering, Faculty of Engineering, University of Nottingham, University Park, Nottingham NG72RD, UK e-mail:

Abstract

Stent geometries are obtained by topology optimization for minimized compliance under different stenosis levels and plaque material types. Three levels of stenosis by cross-sectional area, i.e., 30%, 40%, and 50% and three different plaque material properties, i.e., calcified, cellular, and hypocellular, were studied. The raw optimization results were converted to clear design concepts and their performance was evaluated by implanting them in their respective stenosed artery types using finite element analysis. The results were compared with a generic stent in similar arteries, which showed that the new designs showed less recoil. This work provides a concept that stents could be tailored to specific lesions in order to minimize recoil and maintain a patent lumen in stenotic arteries.

Publisher

ASME International

Subject

Biomedical Engineering,Medicine (miscellaneous)

Link

http://asmedigitalcollection.asme.org/medicaldevices/article-pdf/doi/10.1115/1.4034880/6238741/med_011_01_011001.pdf

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