Measurements of Velocity and Wall Shear Stress Inside a PTFE Vascular Graft Model Under Steady Flow Conditions

Author:

Loth F.1,Jones S. A.2,Giddens D. P.3,Bassiouny H. S.4,Glagov S.5,Zarins C. K.6

Affiliation:

1. Department of Mechanical Engineering, University of Illinois at Chicago, 842 W. Taylor Street (M/C 251), Chicago, IL 60607-7022

2. Department of Biomedical Engineering. The Johns Hopkins University, Baltimore, MD

3. Department of Mechanical Engineering. The Johns Hopkins University, Baltimore, MD

4. Department of Surgery. The University of Chicago, Chicago, IL

5. Department of Pathology. The University of Chicago, Chicago, IL

6. Department Surgery, Stanford University, Palo Alto, CA

Abstract

The flow field inside a model of a polytetrafluoroethylene (PTFE) canine artery end-to-side bypass graft was studied under steady flow conditions using laser-Doppler anemometry. The anatomically realistic in vitro model was constructed to incorporate the major geometric features of the in vivo canine anastomosis geometry, most notably a larger graft than host artery diameter. The velocity measurements at Reynolds number 208, based on the host artery diameter, show the flow field to be three dimensional in nature. The wall shear stress distribution, computed from the near-wall velocity gradients, reveals a relatively low wall shear stress region on the wall opposite to the graft near the stagnation point approximately one artery diameter in axial length at the midplane. This low wall shear stress region extends to the sidewalls, suture lines, and along the PTFE graft where its axial length at the midplane is more than two artery diameters. The velocity distribution inside the graft model presented here provides a data set well suited for validation of numerical solutions on a model of this type.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

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