Effects of Alexidine·2HCl Mouthwash on Plaque and Gingivitis after six Months-Reference-Cited by-同舟云学术

Effects of Alexidine·2HCl Mouthwash on Plaque and Gingivitis after six Months

Published:1977-11 Issue:11 Volume:56 Page:1349-1358
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Spolsky Vladimir W.¹,Forsythe Alan B.¹

Affiliation:

1. Section of Preventive Dentistry and Public Health, School of Dentistry; Health Sciences Computer Facility, University of California at Los Angeles, Center for the Health Sciences, Los Angeles, California 90024, USA

Abstract

Two-hundred and fourteen subjects ranging in age from 22 to 63 years used either a mouthwash that contained 0.035% w/v alexidine· 2HCl (2-ethylhexyl bisbiguanidine dihydrochloride) or a placebo twice daily on a double-blind basis for six months in conjunction with routine oral hygiene procedures. The results indicated that alexidine·2HCl was safe and was statistically more effective in producing a clinically significant reduction in gingivitis than was the placebo.

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/00220345770560111101

Reference13 articles.

1. Inhibitory Effect of a Synthetic Antibiotic Mouthwash (QR-711) on Dental Plaque and Gingivitis in Young Adults

2. Peterson, J.K., and Casad, R.J.: Effects of an Anti-Bacterial Mouthrinse on Gingivitis and Dental Plaque , abstracted, IADR Program and Abstracts of Papers, No. 824, p 258, 1972 .

3. The Effect of an Antimicrobial Mouthwash on Dental Plaque and Gingivitis in Young Adults

4. The Periodontal Disease Index (PDI)

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