Effect of Dopamine on Plasma Growth Hormone and Prolactin Concentrations under Anaesthesia-Reference-Cited by-同舟云学术

Effect of Dopamine on Plasma Growth Hormone and Prolactin Concentrations under Anaesthesia

Published:1988-11 Issue:6 Volume:16 Page:403-412
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Mikawa K.¹,Kusunoki M.²,Obara H.¹,Iwai S.¹

Affiliation:

1. Department of Anaesthesiology, Kobe University School of Medicine, Kusunokicho 7, Chuoku, Kobe 650, Japan

2. Second Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya 663, Japan

Abstract

Five patients with acromegaly and five patients with prolactinoma undergoing general anaesthesia were studied. Concentrations of plasma growth hormone in patients with acromegaly and concentrations of plasma prolactin in patients with prolactinoma were measured before anaesthesia, when 250 mg levodopa was administered orally, and after anaesthesia when dopamine was infused intravenously at a rate of 5 μg/kg-min. There was no difference in hormonal (growth hormone or prolactin) response to either treatment in the anaesthetized and the awake states. These findings indicate that the functioning of dopamine receptors in the anterior pituitary is not affected by anaesthesia.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030006058801600601

Reference33 articles.

1. Binding of Dopamine to Bovine Anterior Pituitary Gland Membranes

2. Multiple receptors for dopamine

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