The Anti-Inflammatory Action of Flurbiprofen Suppositories in Paediatric Urology in Comparison with Co-Trimoxazole

Abstract

Fifty male children, aged between 3 and 10 years, were treated for a 12-day period with either trimethoprim (80–160 mg) plus sulphamethoxazole (400–800 mg) daily (co-trimoxazole) or 50–125 mglday flurbiprofen rectally. The patients had been treated surgically for criptorchidism. Flurbiprofen showed good effectivity in controlling post-operative inflammation in urology. It is concluded that antimicrobial agents such as co-trimoxazole, because of their potential risks of damage at the cell's level, should be used only in presence of a bacterial infection.