Relationship between dietary pattern and cognitive function in elderly patients with type 2 diabetes mellitus

Author:

Enomoto Mari1,Yoshii Hidenori1,Mita Tomoya23,Sanke Haruna2,Yokota Ayako1,Yamashiro Keiko1,Inagaki Noriko1,Gosho Masahiko4,Ohmura Chie2,Kudo Kayo5,Watada Hirotaka2467,Onuma Tomio1

Affiliation:

1. Department of Medicine, Diabetology and Endocrinology, Juntendo Tokyo Koto Geriatric Medical Centre, Tokyo, Japan

2. Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan

3. Centre for Molecular Diabetology, Juntendo University Graduate School of Medicine, Tokyo, Japan

4. Department of Clinical Trials and Clinical Epidemiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan

5. Department of Medicine, Nutritional Management Section, Juntendo Tokyo Koto Geriatric Medical Centre, Tokyo, Japan

6. Centre for Therapeutic Innovations in Diabetes, Tokyo, Japan

7. Sportology Centre, Juntendo University Graduate School of Medicine, Tokyo, Japan

Abstract

Objective To analyse the relationships between dietary patterns and cognitive function in elderly patients with type 2 diabetes mellitus (T2DM). Methods Patients with T2DM completed a 3-day dietary record and Mini-mental State Examination (MMSE). Dietary patterns were identified by factor analysis. Results The study included 73 patients and identified five dietary patterns, one of which was characterized by high loading for vegetables and fish. A higher consumption of vegetables and fish was significantly associated with improved MMSE score (unadjusted model, model adjusted for age and sex, and model adjusted for age, sex, education, diabetic nephropathy and alcohol consumption), and decreased prevalence of suspected mild dementia (unadjusted model, model adjusted for age and sex). Conclusions A high score in the vegetables and fish dietary pattern was associated with high MMSE score and low prevalence of suspected mild dementia in elderly patients with T2DM.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

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