A Comparative Trial of Minocin (Minocycline Hydrochloride) and Ampicillin in the Treatment of Acute Exacerbations of Chronic Bronchitis-Reference-Cited by-同舟云学术

A Comparative Trial of Minocin (Minocycline Hydrochloride) and Ampicillin in the Treatment of Acute Exacerbations of Chronic Bronchitis

Published:1975-09 Issue:5 Volume:3 Page:304-308
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Burrow G R F¹,Fox A S²,Daniel R J E³

Affiliation:

1. General Practitioner, Sheffield, England

2. General Practitioner, London, England

3. Deputy Medical Director, Lederle Laboratories, Gosport, England

Abstract

One hundred and fifteen patients suffering from acute exacerbations of chronic bronchitis took part in a double-blind, multicentre, clinical trial designed to compare the therapeutic efficacy and tolerability of ampicillin and minocycline hydrochloride, a new, long-acting, semi-synthetic tetracycline. Both antibiotics were equally successful in treatment, there being no statistically significant difference between the two in any of the parameters studied. Side-effects were few and far between. Only one patient out of the 57 who took minocycline, complained of dizziness.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030006057500300503

Reference9 articles.

1. SUSCEPTIBILITY OF MYCOPLASMA PNEUMONIAE TO 21 ANTIBIOTICS IN VITRO*

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3. Ampicillin in the Treatment of Haemophilus influenzae Infections of the Respiratory Tract

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