Intravitreal fluocinolone acetonide implant (ILUVIEN®) for diabetic macular oedema: a literature review-Reference-Cited by-同舟云学术

Intravitreal fluocinolone acetonide implant (ILUVIEN®) for diabetic macular oedema: a literature review

Published:2018-12-16 Issue:1 Volume:47 Page:31-43
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Massa Horace¹²^ORCID,Nagar Anindyt M.³²,Vergados Athanasios³,Dadoukis Panagiotis³,Patra Sudeshna³,Panos Georgios D.³^ORCID

Affiliation:

1. Department of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland

2. *These authors contributed equally to this work.

3. Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK

Abstract

Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy and may lead to severe visual loss. In this review, we describe the pathophysiology of DMO and review current therapeutic options such as macular laser photocoagulation, anti-vascular endothelial growth factor agents, and steroid implants with a focus on the new fluocinolone acetonide implant, ILUVIEN®. The results of the Fluocinolone Acetonide in Diabetic Macular Edema (FAME) studies are also presented together with the results of real-world studies to support the clinical use of ILUVIEN® in achieving efficient resolution of DMO and improving vision and macular anatomy in this challenging group of patients.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0300060518816884

Reference57 articles.

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2. Lobo C, Pires I and Cuncha-Vaz J. Diabetic macular edema. In: Bernardes R, Cuncha-Vaz J (eds) Optical Coherence Tomography: A Clinical and Technical Update. Berlin: Spinger Verlag, 2012, pp.1–21.

3. Global Prevalence and Major Risk Factors of Diabetic Retinopathy

4. Diabetic Macular Edema: Pathophysiology and Novel Therapeutic Targets

5. The Wisconsin Epidemiologic Study of Diabetic Retinopathy XV

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