Comparative Study of the Antipyretic Effect of Ibuprofen (Oral Suspension) and Paracetamol (Suppositories) in Paediatrics

Author:

Wilson Guilherme1,Guerra Antonio Jose M. S.2,Santos Norberto Teixeira3

Affiliation:

1. Complementary Resident Paediatrician, 5th year, Hospital of S. Joao, Oporto, Portugal

2. Complementary Resident Paediatrician, 4th year. Hospital of S. Joao, Oporto, Portugal

3. Professor of Social and Clinical Paediatrics, Faculty of Medicine, Oporto, Portugal

Abstract

Thirty-five pyrexial children with varying pathologies were entered into an open study to compare the antipyretic effect of Ibuprofen oral suspension and paracetamol suppositories. Temperature was recorded at intervals up to 11 hours after dosing. It was found that both treatments had an antipyretic effect, but that the magnitude and duration of the antipyretic effect was greater with ibuprofen.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

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