Possible Potential Effects of Honey and Its Main Components Against Covid-19 Infection

Author:

Abedi Farshid1,Ghasemi Saeedeh2,Farkhondeh Tahereh34,Azimi-Nezhad Mohsen56,Shakibaei Mehdi7,Samarghandian Saeed8ORCID

Affiliation:

1. Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran

2. Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran

3. Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran

4. Faculty of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran

5. Non-Communicable Disease Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran

6. UMR INSERM U 1122, IGE-PCV, Interactions Gène-Environment En Physiopathologie Cardiovascular Université De Lorraine, Nancy, France

7. Musculoskeletal Research Group and Tumour Biology, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Munich, Germany

8. Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran

Abstract

Coronavirus disease 2019 (COVID-19) is a viral pneumonia that is spreading rapidly worldwide. The main feature of this disease is a severe acute respiratory syndrome and caused by coronavirus 2 (SARS-CoV-2). There are several unknowns about the pathogenesis and therapeutically treatment of COVID-19 infection. In addition, available treatment protocols have not been effective in managing COVID-19 infection. It is proposed that natural anti-oxidants such as lemon, green tea, saffron, curcuma longa, etc. with high flavonoids like safranal, crocin, crocetin, catechins, resveratrol, calebin A, curcumin have therapeutic potential against viral infections. In this context, honey and its main components are being investigated as an option for patients with COVID-19. The present study may indicate that honey and its main components inhibit the entry of the virus into the host cell and its replication as well as modulate the inflammatory cascade. This review provides basic information for the possible potential effects of honey and its main components for fighting with SARS-CoV-2.

Publisher

SAGE Publications

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Toxicology

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