Renal Secondary Hyperparathyroidism in Aged Sprague-Dawley Rats-Reference-Cited by-同舟云学术

Renal Secondary Hyperparathyroidism in Aged Sprague-Dawley Rats

Published:1977-09 Issue:5 Volume:14 Page:463-469
ISSN:0300-9858
Container-title:Veterinary Pathology
language:en
Short-container-title:Vet Pathol

Author:

Itakura C.¹,Iida M.¹,Goto M.¹

Affiliation:

1. Department of Veterinary Pathology, Faculty of Agriculture, Tottori University, Tottori-shi; and Research and Development Division, Dainippon Pharmaceutical Co., Ltd., Osaka, Japan

Abstract

Fourteen aged Sprague-Dawley rats had typical renal secondary hyperparathy-roidism. The renal disease was severe glomerulosclerosis with tubular dilation. The parathyroid glands were enlarged and had hyperplasia of chief cells. Bone lesions were generalized osteodystrophia fibrosa and osteosclerosis. All rats had osteodystrophia fibrosa and it was severe in 10 rats. Only four rats had osteosclerosis and it was moderate. Metastatic calcification was seen in various soft tissues in 13 rats.

Publisher

SAGE Publications

Subject

General Veterinary

Link

http://journals.sagepub.com/doi/pdf/10.1177/030098587701400505

Reference15 articles.

1. Kidney disease and nutrition in the rat

2. Weitere Untersuchungen zur experimentellen Ostitis fibrosa

3. Ultrastructural Observations of Chronic Progressive Nephrosis in the Sprague-Dawley Rat

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