Severe Ethylene Glycol Butyl Ether Poisoning. Kinetics and Metabolic Pattern-Reference-Cited by-同舟云学术

Severe Ethylene Glycol Butyl Ether Poisoning. Kinetics and Metabolic Pattern

Published:1988-03 Issue:2 Volume:7 Page:187-189
ISSN:0144-5952
Container-title:Human Toxicology
language:en
Short-container-title:Human Toxicology

Author:

Rambourg-Schepens M.O.¹,Buffet M.¹,Bertault R.¹,Jaussaud M.¹,Journe B.¹,Fay R.²,Lamiable D.²

Affiliation:

1. Centre Anti-Poisons, S.A.M.U., Hospital de la Maison Blanche. 51092 Reims cedex, France

2. Laboratoire de Pharmacologie-Toxicologie, Hopital de la Maison Blanche, 51092 Reims Cedex, France

Abstract

A case of severe poisoning with ethylene glycol butyl ether (EGBE) after massive ingestion is described. Deep coma, metabolic acidosis, hypokalaemia, haemoglobinuria, oxaluria and a transitory rise in the serum creatinine level were observed. The elimination of the various metabolites butoxyacetic acid and oxalate was assessed in urine and a metabolic pattern for EGBE is suggested.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://journals.sagepub.com/doi/pdf/10.1177/096032718800700215

Reference4 articles.

1. Analyses of ethylene glycol monoalkyl ethers and their proposed metabolites in blood and urine.

2. n-Butoxyacetic Acid, a Urinary Metabolite from Inhaled n-Butoxyethanol (Butylcellosolve)

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