The Role of In Vitro Experiments in Animal Welfare-Reference-Cited by-同舟云学术

The Role of In Vitro Experiments in Animal Welfare

Published:1993-11 Issue:6 Volume:12 Page:522-527
ISSN:0960-3271
Container-title:Human & Experimental Toxicology
language:en
Short-container-title:Hum Exp Toxicol

Author:

Rasmussen Eva Selzer¹

Affiliation:

1. National Food Agency of Denmark, 19 Mørkhøj Bygade, DK-2860 Søborg, Denmark

Abstract

The prospects of replacing animal experiments with other types of toxicological studies are considered, and the use of human data and in vitro experiments are discussed. Ongoing validation studies of in vitro methods for evaluation of acute toxicity, local irritation, target organ toxicity, tumour promotion and teratogenicity are presented.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/096032719301200610

Reference31 articles.

1. Structural requirements for initiation ofLimulusamebocyte lysate gelation by lipoteichoic acids

2. Survey of the QSAR and in vitro approaches for developing non-animal methods to supersede the in vivo LD50 test

3. Validation of In Vitro Cytotoxicity Tests — Past and Present Strategies

4. The frame interlaboratory programme on in vitro cytotoxicology

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