Cardiopulmonary bypass technique in sheep

Author:

Noera G.1,Fattori G.2,Incerti Medici A.2,Gatti MA2

Affiliation:

1. Institute of Thoracic Surgery

2. Laboratory of Biomaterials, University of Modena

Abstract

During the past two years at the University of Modena, 72 sheep underwent cardiopulmonary bypass (CPB) for various open-heart surgical procedures. An effective protocol for anaesthesia and CPB was developed in these animals. Routine barbiturate induction and maintenance anaesthesia with isofluorane and a pressure-regulated ventilator have minimized anaesthetic problems. The type of priming fluid used was the major factor in overcoming the problems associated with haemodilution effects, clotting insufficiency and postperfusion lung syndrome. Pump flows of 60ml.kg -1 bodyweight.min-1 seem to give adequate circulatory support during heart-lung bypass. A technical report and the pharmacological support protocols used successfully in 66 of the 72 animals during a two-year period are presented.

Publisher

SAGE Publications

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Safety Research,Radiology, Nuclear Medicine and imaging,General Medicine

Reference6 articles.

1. Anesthesia and Cardiopulmonary Bypass Technique in Calves and Sheep

2. Influence of body position on regional pulmonary arterial-venous shunts in intact dogs.

3. Olsen DB Cardiopulmonary bypass for implantation of an artificial heart and for cardiac transplantation. In: Slatter D ed, Textbook of small animal surgery, WB Saunders, 1984: 1141-47.

4. Cardiac surgery in young pigs

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