Transcranial Alternating Current Stimulation Alters Auditory Steady-State Oscillatory Rhythms and Their Cross-Frequency Couplings-Reference-Cited by-同舟云学术

Transcranial Alternating Current Stimulation Alters Auditory Steady-State Oscillatory Rhythms and Their Cross-Frequency Couplings

Published:2023-06-12 Issue: Volume: Page:
ISSN:1550-0594
Container-title:Clinical EEG and Neuroscience
language:en
Short-container-title:Clin EEG Neurosci

Author:

de la Salle Sara¹²^ORCID,Choueiry Joëlle¹³,Payumo Mark⁴,Devlin Matt²,Noel Chelsea²^ORCID,Abozmal Ali²,Hyde Molly¹³,Baysarowich Renée¹³,Duncan Brittany¹,Knott Verner¹²³⁴^ORCID

Affiliation:

1. Clinical Neuroelectrophysiology and Cognitive Research, The Royal's Institute of Mental Health Research, Ottawa, ON, Canada

2. Faculty of Medicine, School of Psychology, University of Ottawa, Ottawa, ON, Canada

3. Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada

4. School of Psychology, Carleton University, Ottawa, ON, Canada

Abstract

Auditory cortical plasticity deficits in schizophrenia are evidenced with electroencephalographic (EEG)-derived biomarkers, including the 40-Hz auditory steady-state response (ASSR). Aiming to understand the underlying oscillatory mechanisms contributing to the 40-Hz ASSR, we examined its response to transcranial alternating current stimulation (tACS) applied bilaterally to the temporal lobe of 23 healthy participants. Although not responding to gamma tACS, the 40-Hz ASSR was modulated by theta tACS (vs sham tACS), with reductions in gamma power and phase locking being accompanied by increases in theta-gamma phase–amplitude cross-frequency coupling. Results reveal that oscillatory changes induced by frequency-tuned tACS may be one approach for targeting and modulating auditory plasticity in normal and diseased brains.

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/15500594231179679

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