Feasibility and Safety of Accelerated Sequential Theta Burst Stimulation for Adolescent Obsessive-compulsive Disorder: A Case Report

Author:

Joseph Jithin Thekkelkuthiyathottil1ORCID,Jammigumpula Ashok1ORCID,Prakash Anjali2,Radhakrishna Amrtavarshini2,Jaise Jithin1,Naik Prathvi1,Purohith Abhiram N.1ORCID,Shenoy Sonia1ORCID,Praharaj Samir Kumar1ORCID

Affiliation:

1. Clinical Research Centre for Neuromodulation in Psychiatry, Department of Psychiatry, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India

2. Department of Psychiatry, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been shown to be effective for treatment-resistant obsessive-compulsive disorder (OCD) in adults; however, it has not yet been studied in adolescents with OCD. This report details the feasibility and safety of administering sequential accelerated theta burst stimulation (sequential aTBS) in an adolescent with treatment-resistant OCD. Despite completing 29 continuous TBS sessions over the right dorsolateral prefrontal cortex (DLPFC) and an additional 15 intermittent TBS sessions on the left DLPFC, our patient did not show any symptom improvement. This case represents the first documentation of the feasibility, safety, and tolerability of sequential aTBS in adolescents with OCD. The patient tolerated the aTBS sessions well, experiencing only mild tingling and local muscle twitches.

Publisher

SAGE Publications

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