Markov Influence Diagrams

Author:

Díez Francisco J.1234,Yebra Mar1234,Bermejo Iñigo1234,Palacios-Alonso Miguel A.1234,Calleja Manuel Arias1234,Luque Manuel1234,Pérez-Martín Jorge1234

Affiliation:

1. Department Artificial Intelligence, UNED, Madrid, Spain (FJD, MA, ML, JP)

2. Centre for Biomedical Technology, Technical University of Madrid, Spain (MY)

3. School of Health and Related Research, University of Sheffield, UK (IB)

4. Computer Science Department, National Institute for Astrophysics, Optics and Electronics, Tonantzintla, Puebla, Mexico (MAP)

Abstract

Markov influence diagrams (MIDs) are a new type of probabilistic graphical model that extends influence diagrams in the same way that Markov decision trees extend decision trees. They have been designed to build state-transition models, mainly in medicine, and perform cost-effectiveness analyses. Using a causal graph that may contain several variables per cycle, MIDs can model various patient characteristics without multiplying the number of states; in particular, they can represent the history of the patient without using tunnel states. OpenMarkov, an open-source tool, allows the decision analyst to build and evaluate MIDs—including cost-effectiveness analysis and several types of deterministic and probabilistic sensitivity analysis—with a graphical user interface, without writing any code. This way, MIDs can be used to easily build and evaluate complex models whose implementation as spreadsheets or decision trees would be cumbersome or unfeasible in practice. Furthermore, many problems that previously required discrete event simulation can be solved with MIDs; i.e., within the paradigm of state-transition models, in which many health economists feel more comfortable.

Publisher

SAGE Publications

Subject

Health Policy

Reference30 articles.

1. Howard RA, Matheson JE. Influence diagrams. In: Howard RA, Matheson JE, eds. Readings on the Principles and Applications of Decision Analysis. Menlo Park, CA: Strategic Decisions Group; 1984:719–62.

2. The Problem of Embedded Decision Nodes in Cost-Effectiveness Decision Trees

3. Kuntz KM, Weinstein MC. Modelling in Economic Evaluation. In: Drummond MF, McGuire A, eds. Economic Evaluation in Health Care. New York: Oxford University Press; 2001:141–71.

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