Pharmacokinetic and Pharmacodynamic Consequences of Metabolism‐Based Drug Interactions with Alprazolam, Midazolam, and Triazolam

Author:

Yuan Rae1,Flockhart David A.2,Balian John D.1

Affiliation:

1. Department of Office of Clinical Pharmacology and Biopharmaceutics, Center for Drug Evaluation and Research, U.S. Food and Drug Administration (USFDA), Rockville, Maryland

2. Department of Medicine and Pharmacology, Division of Clinical Pharmacology, Georgetown University Medical Center, Washington, D.C.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference93 articles.

1. Incidence of Adverse Drug Reactions in Hospitalized Patients

2. Drug metabolism by cytochromes P450 in the liver and small bowel;Watkins P;Gastroenterology Clinics of North America,1992

3. The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: A population study*

4. In vitro metabolism of terfenadine by a purified recombinant fusion protein associated with CYP3A(4) activity and NADPH‐P450 reductase;Rodrigues AD;Drug Metab Dispos,1995

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