Linezolid: Pharmacokinetic and Pharmacodynamic Evaluation of Coadministration with Pseudoephedrine HCl, Phenylpropanolamine HCl, and Dextromethorphan HBr

Author:

Hendershot Pamela E.,Antal Edward J.,Welshman Ian R.,Batts Donald H.,Hopkins Nancy K.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference27 articles.

1. Martin JP Herberg JT Slatter JG Dupuis MJ Although a novel microtiter-plate assay demonstrates that linezolid (PNU-100766) is a weak, competitive (reversible) inhibitor of human monoamine oxidase (MAO A), no clinical evidence of MAO A inhibition in clinical trials has been observed September 1998

2. Pawsey SD Daley-Yates PT Wajszczuk CP Stalker DJ U-100766 Safety, toleration and pharmacokinetics after oral and intravenous administration [abstract F151] May 1996

3. Feenstra KL Slatter JG Stalker DJ Welshman IR Hauer MJ Cathcart KS et al Metabolism and excretion of the oxazolidinone antibiotic linezolid (PNU-100766) following oral administration of [ 14 C]PNU-100766 to healthy volunteers September 1998

4. Stalker DJ Wajszczuk CP Batts DH Linezolid safety, tolerance, and pharmacokinetics following oral dosing twice daily for 14.5 days September 1997

5. A pharmacokinetic evaluation of concomitant administration of linezolid and aztreonam;Sisson;J Clin Pharmacol,1999

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