The Significance of Lysosomal Enzymes in Middle Ear Effusions

Author:

Bernstein Joel M.1,Villari Elizabeth M.2,Rattazzi Mario C.3

Affiliation:

1. Departments of Otolaryngology and Microbiology, State University of New York at Buffalo

2. Pediatrics, State University of New York at Buffalo

3. Pediatrics, State University of New York at Buffalo, New York

Abstract

Although lysosomal enzymes have been demonstrated in middle ear effusions by several investigations, the exact source of these enzymes and the role they play in the maintenance and progression of otitis media with effusion have not been thoroughly studied. The source of lysososmal enzymes in middle ear fluids and their possible role in the inflammatory process in otitis media with effusion are explored.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Upregulation of Messenger RNA for Inflammatory Cytokines in Middle Ear Mucosa in a Rat Model of Acute Otitis Media;Annals of Otology, Rhinology & Laryngology;1998-06

2. Expression of Acute Otitis Media after Receptor Blockade of Platelet Activating Factor, Thromboxane, and Leukotrienes in the Chinchilla;Annals of Otology, Rhinology & Laryngology;1998-03

3. Treatment of experimental acute otitis media with ibuprofen and ampicillin;International Journal of Pediatric Otorhinolaryngology;1995-10

4. Otites séreuses et allergie;Revue Française d'Allergologie et d'Immunologie Clinique;1994-04

5. Middle Ear Fluid Lysozyme Source in Experimental Pneumococcal Otitis Media;Annals of Otology, Rhinology & Laryngology;1991-07

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