Reduction of Pharyngocutaneous Fistulae in Laryngectomy Patients by a Comprehensive Performance Improvement Intervention

Author:

Li Ryan J.1,Zhou Xian Chong2,Fakhry Carole13,Negrin Juan3,Lee Gregory3,Ha Patrick13,Blanco Ray13,Saunders John13,Califano Joseph A.134

Affiliation:

1. Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

2. Department of Oncology–Biostatistics, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

3. Milton J. Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, USA

4. Division of Otolaryngology–Head and Neck Surgery, Department of Surgery, University of California, San Diego, La Jolla, California, USA

Abstract

Objective Pharyngocutaneous fistula is a common complication in laryngectomy patients, particularly in previously irradiated cases. We initiated a comprehensive performance improvement intervention in all head and neck surgery patients intended to reduce postoperative infection and fistulae rates. We report our review of outcomes within laryngectomy patients. Study Design Case series with chart review. Setting Academic tertiary referral center. Subjects Nineteen laryngectomy patients at risk of postoperative fistula formation. Methods We reviewed the medical records of all patients who had undergone laryngectomy procedures between January 2013 and April 2014. Clinicodemographic data were obtained, including history of diabetes, prior radiation therapy, type of reconstruction performed for closure of the pharyngeal defect, and the presence or absence of postoperative fistula. Results The study population comprised 19 laryngectomy patients. Prior to implementation of our performance improvement intervention, 8 of 11 (73%) patients undergoing laryngectomy developed postoperative fistulae. After intervention, 0 of 8 patients developed fistulae ( P = .002). Prior radiation, diabetes mellitus, and overall stage were not associated with a reduction in fistula rate ( P > .05). Conclusion Comprehensive uniform application of a standard antibiotic prophylaxis, surgical technique, perioperative care, and treatment of comorbid conditions can significantly reduce and potentially eliminate fistulae in laryngectomy patients who are especially at risk.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

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