Paget’s disease of bone: a review of epidemiology, pathophysiology and management

Author:

Shaker Joseph L.1

Affiliation:

1. Medical College of Wisconsin, W129 N7055 Northfield Drive, Building A, Suite 203, Menomonee Falls, WI 53051, USA,

Abstract

Paget’s disease of bone is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. Fortunately, effective pharmacologic therapy, primarily with potent bisphosphonates, is now available to treat patients with complications or symptoms. This review of Paget’s disease of bone will include epidemiology and pathophysiology, complications and clinical findings, indications for treatment, and the drugs currently available to treat this condition.

Publisher

SAGE Publications

Subject

Orthopedics and Sports Medicine,Rheumatology

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